In this database, the following information about F. graminearum can be found.
Gene information - basic information of genes including the name, synonyms, location in genomes and nucleic acid sequence from FGDB database.
Function - functional annotation of genes from FGDB database.
Promoter sequence - the upstream 1000bp nucleic acid sequence from the transcription start site of corresponding genes.
Protein information - basic information of proteins including amino acid sequence, protein functional annotation, and domain composition scanned with InterProScan.
Subcellular localization - subcellular location information of proteins predicted previously (details can be found here).
Pathogenic genes - the genes that affect the host infection of F. graminearum, including known pathogenic genes from literature and predicted pathogenic genes
Transcription factors (TFs) - the list of TFs identified within F. graminearum.
Enzyme - proteins with known enzyme catalytic activity obtained from KEGG database.
Pathway - the pathway annotation of proteins within F. graminearum in KEGG database.
Gene ontology (GO) annotation - the GO annotation of genes and proteins within F. graminearum from EBI database.
Protein-protein interactions - the list of interacting protein pairs, including core PPIs set and all PPIs set where the core PPIs set includes the high confident interactions while the all PPIs set is composed of all predicted interactions between proteins in F. graminearum.
Orthologs - the orthologs of F. graminearum proteins in 24 other well studied model organisms (see below) as well as their best hit in 4 popular public databases: NR, UniProt, COGs and MEROPS.
Blastomyces dermatitidis | Botrytis cinerea | Caenorhabditis elegans | Candida albicans sc5314 |
Candida albicans wo1 | Candida tropicalis | Coccidioides immitis | Coccidioides posadasii |
Cryptococcus neoformans | Drosophila melanogaster | Escherichia coli | Fusarium oxysporum |
Histoplasma capsulatum | Homo sapiens | Magnaporthe grisea | Mus musculus |
Pyrenophora tritici | Saccharomyces cerevisiae RM11-1a | Saccharomyces cerevisiae S288c | Schizosaccharomyces pombe |
Sclerotinia sclerotiorum | Stagonospora nodorum | Ustilago maydis | Verticillium dahliae |
Gene expression - the transcript expression data deposited in GEO database and PLEXdb.
Database |
ID |
Platform |
Short Description |
GEO |
GSE36638 | NimbleGen Fusarium_tiling_300k_V1 | Genome-wide expression profiling in a Fusarium graminearum lacking FgVelB, a velvet complex gene |
GSE30545 | Roche Nimblegen G.zeae 135K microarray | Genome-wide expression profiling reveals transcriptional reprogramming in Fusarium graminearum by FgV1-DK21 virus infection | |
GSE24636 | Fusarium graminearum 4×44k | Effect of salicylic acid on Fusarium graminearum, the major causal agent of fusarium head blight in wheat | |
GSE30892 | Fusarium graminearum 4×44k | Tri6 is a global transcription regulator in the phytopathogen Fusarium graminearum | |
GSE29973 | Fusarium graminearum febit in situ oligonucleotide array | Transcriptional responses of Fusarium graminearum to plant cell wall substrates | |
GSE25114 | 021301-MLU Fusarium graminearum 8×15K v1.0 | Genome-wide expression profiling of Fusarium graminearum in response to azole fungicide treatmen | |
PLEXdb |
FG1 | F. graminearum Affymetrix GeneChip | Fusarium transcript detection on Morex barley spikes using Fusarium Affy GeneChips |
FG2 | F. graminearum Affymetrix GeneChip | Expression Profiles in Carbon and Nitrogen Starvation Conditions | |
FG3 | F. graminearum Affymetrix GeneChip | Cross-species hybridization | |
FG4 | F. graminearum Affymetrix GeneChip | Fusarium/Barley RNA dilution | |
FG5 | F. graminearum Affymetrix GeneChip | Fusarium transcript detection during in vitro sexual development using Fusarium Affy GeneChips | |
FG6 | F. graminearum Affymetrix GeneChip | Transcript detection during in vitro sexual development of Fusarium Cch1 calcium channel deletion mutant using Fusarium Affy GeneChips | |
FG7 | F. graminearum Affymetrix GeneChip | Fusarium gene expression profiles during conidia germination stages | |
FG10 | F. graminearum Affymetrix GeneChip | Response to trichodiene treatment in Fusarium graminearum | |
FG11 | F. graminearum Affymetrix GeneChip | Gene Regulation by Fusarium Transcription Factors Tri6 and Tri10 | |
FG12 | F. graminearum Affymetrix GeneChip | Fusarium graminearum gene expression during crown rot of wheat | |
FG13 | F. graminearum Affymetrix GeneChip | The transcription factor FgStuAp influences spore development, pathogenicity and secondary metabolism in Fusarium graminearum | |
FG14 | F. graminearum Affymetrix GeneChip | DON induction media | |
FG15 | F. graminearum Affymetrix GeneChip | F. graminearum gene expression during wheat head blight | |
FG16 | F. graminearum Affymetrix GeneChip | Fusarium graminearum gene expression in wheat stems during infection | |
FG18 | F. graminearum Affymetrix GeneChip | Trichothecene synthesis in a Fusarium graminearum Fgp1 mutant | |
FG19 | F. graminearum Affymetrix GeneChip | Stage-specific expression patterns of Fusarium graminearum growing inside wheat coleoptiles with laser microdissection | |
NF1 | F. graminearum Affymetrix GeneChip | Wheat infection by a Fusarium graminearum Fgp1 mutant | |
NF6 | F. graminearum Affymetrix GeneChip | Gene expression during vegetative growth in complete liquid medium of Fusarium graminearum and Fusarium oxysporum and corresponding mutants in orthologous WOR1-like genes. (NineFungalArray_Fus_gra) | |
NF7 | F. graminearum Affymetrix GeneChip | Gene expression during vegetative growth in complete liquid medium of Fusarium graminearum and Fusarium oxysporum and corresponding mutants in orthologous WOR1-like genes (NineFungalArray_Fus_oxy) |
Note that, in this database, the subcellular location, protein-protein interaction and parts of pathogenic genes were predicted as described in our prior works [1-3]. The gene information, functional annotation, promoter sequence and amino acid sequence were collected from FGDB database[4]. The domain composition of proteins was scanned with the InterProScan[5]. The known pathogenic genes were collected from the PHI-base database[6]. Transcription factors were obtained from [7]. The enzyme catalytic activity and pathway information of F. graminearum proteins were collected from KEGG database[8]. The orthologs of F. graminearum proteins were identified in 24 species by utilizing Inparanoid software[9], and the best hit(s) of each proteinin 4 public databases: NR[10], UniProt[11], COGs[12] and MEROPS[13], was obtained with BLAST[14].